CDC reports rare vaccinia infection in vaccinated lab worker

first_imgA laboratory worker in Boston was infected with vaccinia virus because of a needlestick injury, despite having been vaccinated against the virus 10 months earlier, according to an article today in Morbidity and Mortality Weekly Report.The article says the infection is the first reported in a US lab worker who had been vaccinated recently in accord with recommendations of the Advisory Committee on Immunization Practices (ACIP). Vaccinia is the virus used in smallpox vaccines.Initial presentation, treatmentThe worker, a 27-year-old staff member in an academic institution, accidentally pricked his thumb on Nov 17, 2013, while recapping a needle he had been using to inoculate an anesthetized mouse with wild-type vaccinia virus, according to the report. He said the mishap occurred when he was distracted by the movement of a mouse in another cage.The worker immediately washed his hands for about 10 minutes while expressing blood from the wound. A report on the incident was filed the same day, and the man was advised to go to a hospital emergency department immediately if symptoms appeared.Six days later he sought care for a non-tender rash on his left arm, and an ultrasound exam showed a small collection of fluid at the puncture site. He was diagnosed as having cellulitis and given intravenous cefazolin, followed by oral cephalexin. On Nov 25 he reported to his institution’s occupational health clinic with a necrotic lesion at the puncture site along with the arm rash.A necrotic vaccinia virus infection was diagnosed, and the patient was advised to keep taking cephalexin. Two days later the lesion was stable and the arm rash had resolved. On Dec 10, 23 days after the injury, the lesion was surgically debrided, and by Jan 9 the lesion was healed.Specimens sent to a state laboratory and the CDC tested positive for an orthopoxvirus, and the Centers for Disease Control and Prevention identified vaccinia virus by tissue culture.Recapping needles found improperAs required, the occupational health clinic notified the Boston Public Health Commission (BPHC) of the case. The commission visited the lab Nov 26 and found most things in order but identified recapping of needles as a departure from recommended procedures.The patient, who had worked at the lab since January 2013, had received proper training and had received the ACAM2000 smallpox vaccine on Jan 28. A skin lesion at the site showed that the vaccination “took.”A serologic study by the CDC showed that the patient had high levels of orthopoxvirus immunoglobulin G, suggesting earlier exposure to the virus by vaccination or infection, the report says. But the antibody level necessary for protection against the virus is unknown, as was the viral load caused by the injury.The report says the ACIP advises that lab workers who handle wild-type vaccinia viruses should be revaccinated every 10 years. Two previous vaccinia infections have been reported in vaccinated workers, but one of them had been vaccinated more than 10 years before exposure, and the other had been vaccinated 6 years preexposure and did not have a vaccine “take.””Vaccination alone is insufficient as the sole preventive measure against laboratory-acquired orthopoxvirus infections,” the report states. “It must be complemented with effective biosafety protocols such as education of laboratory personnel, safe laboratory practice, and incident reporting.”CDC. Laboratory-acquired vaccinia virus infection in a recently immunized person—Massachusetts, 2013. MMWR 2015 May 1;64(16):435-8 [Full text]last_img read more

H2-powered taxi fleet reaches 100 vehicles

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first_imgGet your free guest access  SIGN UP TODAY Subscribe now for unlimited access Subscribe to Building today and you will benefit from:Unlimited access to all stories including expert analysis and comment from industry leadersOur league tables, cost models and economics dataOur online archive of over 10,000 articlesBuilding magazine digital editionsBuilding magazine print editionsPrinted/digital supplementsSubscribe now for unlimited access.View our subscription options and join our community To continue enjoying Building.co.uk, sign up for free guest accessExisting subscriber? LOGIN Stay at the forefront of thought leadership with news and analysis from award-winning journalists. Enjoy company features, CEO interviews, architectural reviews, technical project know-how and the latest innovations.Limited access to building.co.ukBreaking industry news as it happensBreaking, daily and weekly e-newsletterslast_img read more

Vieille Case wins 2015 Carnival Mother’s Queen

first_img Share Sharing is caring! Share 2014 Carnival Mother’s Queen Heather Vidal of Portsmouth (left) and the 2015 Carnival Mother’s Queen Frances LockhartFrances Lockhart, 28, of Vieille Case is the 2015 Carnival Mother’s Queen.Ms Lockhart outshined six other contestants in the third annual Carnival Mother’s Queen show at the Arawak House of Culture in Roseau on Saturday 7 February.Ms Lockhart, who won the awards for Best evening wear, Best in evening wear and Miss Intelligence, was crowned by Heather Vidal of Portsmouth, the 2014 Carnival Mother’s Queen.Taneka Albert, 21, of Laudat who emerged 1st runner up, won the awards for Best traditional ole masquerade wear and Best in traditional ole masquerade wear.Elloise Etienne, 26, of Kalinago Territory & Stockfarm, placed 2nd runner up and won the awards for Best swimwear, Best in swimwear and Miss Amity.Annadale Jacob, 26, of St Joseph placed 3rd runner up while Kendra Stephen, 30, of Newtown won the Miss photogenic award.The other contestants were Geraldine Davis, 28, of Fond Cole and Lena Durand, 28, of Calibishie.– / 69 Sharecenter_img 529 Views   no discussions EntertainmentLocalNews Vieille Case wins 2015 Carnival Mother’s Queen by: Dominica Vibes News – February 8, 2015 Tweetlast_img read more

Coe praises Carifta Games

first_imgThe history of the Carifta Games is liberally sprinkled with the names of young stars who later became champions at the highest level. That appeal has kept Sebastian Coe, the president of the International Associations of Athletics Federation, coming back to watch the meet year after year. Coe, the 1980 and 1984 Olympic 1500 metre champion, praised the meet at its 48th staging in Grand Cayman last weekend and said that it has emboldened him to do his job as head of the world governing body of athletics.Speaking on Monday, the final day of the Games, Coe reflected: “You know, the best bellwether of any sport is what’s happening in the development programmes, and quintessentially, Carifta is about the development of great, great athletes, and pretty much every athlete who has made it on to the global stage out of the Caribbean has graduated from the Carifta Games.” CARIFTA STANDOUTS The list of Carifta standouts includes Jamaicans Usain Bolt, Veronica Campbell-Brown, Omar McLeod, and Melaine Walker; Bahamians Tonique Williams-Darling, Avard Moncur, and Debbie Ferguson-McKenzie; the Grenadian Kirani James and Jehue Gordon; and Keshorn Walcott of Trinidad and Tobago. “They’ve all come through this,” Coe emphasised.He hopes that his visits will help him to spot the next flight of Caribbean stars.“I just love watching raw talent at the beginning of the journey, and the best audit of the health and vibrancy of any sport is what’s going behind the scenes and who are the young athletes who are going to fill those mighty footprints, and I leave the Carifta [Games] enlivened, emboldened to do my job,” said Coe.He had a word of encouragement for those worried about the future of the sport.“I think I have a privilege because I think I see it years before anyone else does, and I say to people when they say who’s going to follow Usain, who’s going to follow Asafa, and I say, ‘Get your butt to the Carifta Games and answer that question yourself’,” the former world record holder pronounced.Asked about concerns for a star who could pull fans into the sport as Bolt did, he sounded a confident note.“I’m never worried about that because if you were talking to me 20 years ago, 25 years ago, you’d probably be asking me the question, ‘What’s going to happen when Michael Johnson goes? What’s going to happen when Carl Lewis goes? What happens when Daley Thompson goes?’”After laying down that reference to that trio of repeat Olympic champions, he said simply, “We always find great, great athletes.”last_img read more