CDC reports rare vaccinia infection in vaccinated lab worker

first_imgA laboratory worker in Boston was infected with vaccinia virus because of a needlestick injury, despite having been vaccinated against the virus 10 months earlier, according to an article today in Morbidity and Mortality Weekly Report.The article says the infection is the first reported in a US lab worker who had been vaccinated recently in accord with recommendations of the Advisory Committee on Immunization Practices (ACIP). Vaccinia is the virus used in smallpox vaccines.Initial presentation, treatmentThe worker, a 27-year-old staff member in an academic institution, accidentally pricked his thumb on Nov 17, 2013, while recapping a needle he had been using to inoculate an anesthetized mouse with wild-type vaccinia virus, according to the report. He said the mishap occurred when he was distracted by the movement of a mouse in another cage.The worker immediately washed his hands for about 10 minutes while expressing blood from the wound. A report on the incident was filed the same day, and the man was advised to go to a hospital emergency department immediately if symptoms appeared.Six days later he sought care for a non-tender rash on his left arm, and an ultrasound exam showed a small collection of fluid at the puncture site. He was diagnosed as having cellulitis and given intravenous cefazolin, followed by oral cephalexin. On Nov 25 he reported to his institution’s occupational health clinic with a necrotic lesion at the puncture site along with the arm rash.A necrotic vaccinia virus infection was diagnosed, and the patient was advised to keep taking cephalexin. Two days later the lesion was stable and the arm rash had resolved. On Dec 10, 23 days after the injury, the lesion was surgically debrided, and by Jan 9 the lesion was healed.Specimens sent to a state laboratory and the CDC tested positive for an orthopoxvirus, and the Centers for Disease Control and Prevention identified vaccinia virus by tissue culture.Recapping needles found improperAs required, the occupational health clinic notified the Boston Public Health Commission (BPHC) of the case. The commission visited the lab Nov 26 and found most things in order but identified recapping of needles as a departure from recommended procedures.The patient, who had worked at the lab since January 2013, had received proper training and had received the ACAM2000 smallpox vaccine on Jan 28. A skin lesion at the site showed that the vaccination “took.”A serologic study by the CDC showed that the patient had high levels of orthopoxvirus immunoglobulin G, suggesting earlier exposure to the virus by vaccination or infection, the report says. But the antibody level necessary for protection against the virus is unknown, as was the viral load caused by the injury.The report says the ACIP advises that lab workers who handle wild-type vaccinia viruses should be revaccinated every 10 years. Two previous vaccinia infections have been reported in vaccinated workers, but one of them had been vaccinated more than 10 years before exposure, and the other had been vaccinated 6 years preexposure and did not have a vaccine “take.””Vaccination alone is insufficient as the sole preventive measure against laboratory-acquired orthopoxvirus infections,” the report states. “It must be complemented with effective biosafety protocols such as education of laboratory personnel, safe laboratory practice, and incident reporting.”CDC. Laboratory-acquired vaccinia virus infection in a recently immunized person—Massachusetts, 2013. MMWR 2015 May 1;64(16):435-8 [Full text]last_img read more

Fisher-Folk in Saint Lucia, Grenada To Benefit From Post Disaster Insurance

first_img Barbados Maritime Affairs Ministry to Co-Host Upcoming… Hurricane Warning Declared as Tropical Storm Nana Approaches… It explained that the Caribbean Oceans and Aquaculture Sustainability Facility acronym COAST, is an insurance product geared at safeguarding the livelihood of fisher-folk in the aftermath of a natural disaster. Read more at: Saint Lucia Times Share this:PrintTwitterFacebookLinkedInLike this:Like Loading… Sep 29, 2020 Sep 2, 2020 You may be interested in… (Saint Lucia Times) Fisher-Folk in Saint Lucia and Grenada are the first in the Caribbean to be covered under a unique insurance policy post the aftermath of a natural disaster. According to a release from the National Competitiveness and Productivity Council (NCPC), with fisher-folk usually counting their losses post the hurricane season they sense relief is finally at hand. The release noted that a team from the World Bank alongside officials from the Caribbean Catastrophy Risk Insurance Facility (CCRIF SPC) were recently on island to launch the first of its kind insurance policy specific to the fisheries sector.center_img CDB to Lend US$70M to The Bahamas and Saint Lucia,… Aug 24, 2020 CRFM, CDEMA sign agreement to enhance disaster management, resilience in fisheries(CRFM)—The Caribbean Regional Fisheries Mechanism (CRFM) recently signed a memorandum of understanding with the Caribbean Disaster Emergency Management Agency (CDEMA) to enhance comprehensive disaster management and climate change resilience in the fisheries and aquaculture sector within the Caribbean Community (CARICOM). CRFM Executive Director, Milton Haughton, signed the MOU for CRFM…July 31, 2019In “Agriculture”Caribbean Countries to benefit from Partnership to Develop Climate resilient Fisheries and Aquaculture IndustriesThe Caribbean Regional Fisheries Mechanism (CRFM) and CCRIF SPC have signed a Memorandum of Understanding to develop climate-resilient fisheries and aquaculture industries in the region. The purpose of the MOU is to formalise collaboration around the Caribbean Oceans and Aquaculture Sustainability Facility (COAST) initiative, which will help to reduce the…April 15, 2019In “Agriculture”Fisheries Ministers from CRFM Member States meet Friday in GuyanaBelize City (CRFM Press Release)—The Caribbean Regional Fisheries Mechanism (CRFM) will host the 11th Meeting of its Ministerial Council—the highest ranking decision-making body of the regional fisheries organization—starting at 9:00 a.m. on Friday, May 19, at the Pegasus Hotel in Georgetown, Guyana. Ministers who hold the portfolio for fisheries from…May 18, 2017In “CARICOM”Share this on WhatsApp Staunching the flow: St. Kitts and Nevis’ Fight to Keep its… Sep 1, 2020last_img read more

Cook Compression launches Authorised Service Partner Program in Europe

first_imgSubscribe Get instant access to must-read content today!To access hundreds of features, subscribe today! At a time when the world is forced to go digital more than ever before just to stay connected, discover the in-depth content our subscribers receive every month by subscribing to gasworld.Don’t just stay connected, stay at the forefront – join gasworld and become a subscriber to access all of our must-read content online from just $270.last_img

Counsel count cost of Halliwells collapse

first_imgThe protracted demise of Halliwells was set to enter its final chapter on Tuesday as administrators awaited creditor approval for proposals that would see the defunct firm formally wound up. As the Gazette went to press, it remained unclear how much secured creditor Royal Bank of Scotland would recoup in respect of outstanding loans to Halliwells totalling £17.7m. A report published last week by joint administrators from BDO said taxpayer-controlled RBS was not expected to receive the full amount. The report revealed that Halliwells collapsed owing £14.1m to unsecured creditors, including £2.1m owed to barristers and professional experts, including firms of solicitors. Seven QCs are among more than 20 counsel owed five-figure sums. HM Revenue & Customs is owed £4.3m, the highest amount. However, the list includes a wine supplier, a London sandwich bar, and Manchester United and Sheffield United football clubs, among dozens of trading entities both large and small. Unsecured creditors are not expected to receive a dividend but some fortunate barristers could recoup some or all of the amounts owed to them depending on when payments were processed. Manchester-headquartered Halliwells, one of the UK’s biggest regional law firms, collapsed earlier this year following a steep decline in profitability resulting from the recession. Net profit peaked at £8.5m in 2006/07 before the downturn took hold. The firm recorded a loss of £1.8m in 2008/09. It was the policy of the de facto partners, members of a limited liability partnership, to draw remuneration equivalent to the entirety of projected profits, the administrators noted. As they were LLP members, they are not personally liable for the firm’s outstanding debts. BDO has also drawn attention to the legacy of a multi-million-pound reverse premium paid to Halliwells a few years ago when it agreed to move into headquarters in Spinningfields, dubbed Manchester’s ‘Canary Wharf.’ About 75% of that premium, understood to exceed £20m, was distributed to equity partners, most of whom are understood to have left the firm before it fell into administration. The firm was subsequently run on borrowed money, with RBS taking a security over its assets. Halliwells LLP went under with work in progress of £16.3m and debtors totalling £12.1m. The bulk of the firm was carved up by four rivals – Hill Dickinson, Kennedys, Barlow Lyde & Gilbert and HBJ Gateley Wareing – to which most LLP members and staff transferred. The quartet are expected to pay more than £8m in total for the assets they acquired, partly depending on the extent to which outstanding client bills are honoured. The report shows that the administration has so far cost £1.1m, with BDO partners billing at up to £645 an hour, and principals and directors at the accountancy firm at £400-£500 an hour.last_img read more

Wonders & blunders with Roger FitzGerald

first_imgGet your free guest access  SIGN UP TODAY Subscribe now for unlimited access Stay at the forefront of thought leadership with news and analysis from award-winning journalists. Enjoy company features, CEO interviews, architectural reviews, technical project know-how and the latest innovations.Limited access to industry news as it happensBreaking, daily and weekly e-newsletters To continue enjoying, sign up for free guest accessExisting subscriber? LOGIN Subscribe to Building today and you will benefit from:Unlimited access to all stories including expert analysis and comment from industry leadersOur league tables, cost models and economics dataOur online archive of over 10,000 articlesBuilding magazine digital editionsBuilding magazine print editionsPrinted/digital supplementsSubscribe now for unlimited access.View our subscription options and join our communitylast_img read more

Trump says ‘I do regret’ some caustic campaign statements

first_img Do you see a typo or an error? Let us know. Trump says ‘I do regret’ some caustic campaign statements Published: August 19, 2016 5:32 AM EDT SHAREcenter_img CHARLOTTE, N.C. (AP) – In a highly uncharacteristic move aimed at resetting his struggling campaign, Donald Trump has said for the first time that he regrets some of the caustic comments he’s made that may have caused people pain.“Sometimes in the heat of debate and speaking on a multitude of issues, you don’t choose the right words or you say the wrong thing. I have done that,” the GOP nominee, reading from prepared text, said at a rally in Charlotte, N.C. Thursday night. “And believe it or not, I regret it – and I do regret it – particularly where it may have caused personal pain.”Trump didn’t specify what comments he was referring to, but he added that, “Too much is at stake for us to be consumed with these issues.”It was a rare admission for a man who has said that he prefers “not to regret anything” and it underscores the dire situation he finds himself in. With just 80 days left until the election, Trump is trailing Democratic rival Hillary Clinton in preference polls of most key battleground states. At the same time, party leaders have conceded they may divert resources away from the presidential contest in favor of vulnerable Senate and House candidates if things don’t improve.The remarks came a day after Trump announced that he was overhauling his campaign operation, bringing in a new chief executive and appointing a new campaign manager. Rarely do presidential campaigns wait to advertise, or undergo such leadership tumult, at such a late stage of the general election.Yet Trump has struggled badly in recent weeks to offer voters a consistent message, overshadowing formal policy speeches with a steady stream of self-created controversies, including a public feud with an American Muslim family whose son was killed while serving in the U.S. military in Iraq.Trump’s decision to tap Stephen Bannon, a combative conservative media executive, as his new campaign chief suggested to some that he might continue the divisive rhetoric that has angered minorities and alienated large swaths of the general election electorate.Instead, a new Trump emerged on Thursday: a less combative, more inclusive candidate who said he was running to be the “voice for every forgotten part of this country that has been waiting and hoping for a better future” and for those who “don’t hear anyone speaking for them.”And the changes appear to be more than cosmetic. Earlier Thursday, Trump moved to invest nearly $5 million in battleground state advertising to address daunting challenges in the states that will make or break his White House ambitions.The New York businessman’s campaign reserved television ad space over the coming 10 days in Florida, North Carolina, Ohio and Pennsylvania, according to Kantar Media’s political ad tracker. While Clinton has spent more than $75 million on advertising in 10 states since locking up her party’s nomination, Trump’s new investment marks his first of the general election season.Trump also made a last-minute scheduling change, scrapping a planned event in New York in order to travel with his running mate Mike Pence to tour the flood damage in Louisiana on Friday morning.But the visit was met with harsh words from Gov. John Bel Edwards, whose spokesman Richard Carbo said, “We welcome him to LA, but not for a photo-op.”In his remarks, Trump struck a new, inclusive tone and tried to appeal directly to non-white voters, who have so far resisted his candidacy.“I will not rest until children of every color in this country are fully included in the American Dream,” Trump said, urging African-American voters to give him a chance.“What do you have to lose by trying something new?” he asked.Clinton’s campaign, meanwhile, brushed off the speech off as just words he read from a teleprompter.“Donald Trump literally started his campaign by insulting people. He has continued to do so through each of the 428 days from then until now, without shame or regret,” said spokeswoman Christina Reynolds in a statement.“We learned tonight that his speechwriter and teleprompter knows he has much for which he should apologize. But that apology tonight is simply a well-written phrase until he tells us which of his many offensive, bullying and divisive comments he regrets and changes his tune altogether,” she said.It remains to be seen whether Trump’s reboot comes too late, and whether he has the discipline to maintain it.But several Trump supporters at the rally applauded the move.“It takes a lot of strength to say, ‘I’m sorry, ‘ to admit – not that he was wrong, but he wished he hadn’t done it,” said Cindy Ammons, 70, a Trump supporter from Spindale, North Carolina. “I think he’s evolving,” she said.Still, some said it was unnecessary.“I think the regime wanted him to say it. It was damage control,” said Jeff Devers, 46, visiting from Arkansas. “But I personally don’t regret anything that he’s said. What he has said should have been said, politically correct or not.” Author: Associated Press last_img read more

Bar ‘strike’ must not disrupt prosecutions, says DPP

first_imgThe director of public prosecutions has indicated that the Crown Prosecution Service will not make allowances for the criminal bar’s forthcoming protest action.However the most senior judges have issued a note giving the judiciary a degree of latitude to allow adjournments.The Criminal Bar Association announced earlier this month that the first ‘day of action’ by the bar in protest at the government’s cuts to criminal legal aid will be on 6 January – the first day back after the Christmas break. Members of the association have said they will stay away from court on the morning of that day. Following ‘many queries’ about the position of the courts, the lord chief justice Sir John Thomas and the senior presiding judge Lord Justice Gross sent a note to all presiding and resident judges setting out the judiciary’s position in relation to the strike action in order to ‘minimise uncertainty’.It said: ‘The position of the judiciary is straightforward. It is constitutionally independent. Monday 6 is a normal working day and as such, the business of the court will go ahead as normal.’In line with usual practice, the letter said courts should hear any applications to adjourn, taking into account the interests of both parties and the administration of justice. A case should be removed from the list only if an application is made on ‘properly arguable grounds’.But the note appears to give judges some flexibility, stating that each listing decision is a matter for the individual judge taking into account the particular circumstances of the case. The director of public prosecutions Alison Saunders (pictured) says that 6 January will be business as usual.‘We fully understand the anxieties and concerns of the criminal bar at this difficult time, but that does not provide a sufficiently good reason for the work of the prosecution to be disrupted,’ she wrote in a note to heads of chambers. ‘We expect any court business listed for the morning of 6 January to be prosecuted by the instructed advocate(s) in accordance with their professional obligations and that includes part-heard trials and new cases listed, particularly in respect of fixed-date trials.‘If instructions have to be returned for reasons beyond counsel’s control, then we expect chambers to secure alternative counsel of suitable experience and expertise to accept the return.’Given the ‘very good relationship’ that has been built up between the CPS and the criminal bar, Saunders said it would be ‘disappointing’ if prosecution work suffers as a consequence of the bar’s wider concerns about defence funding and quality assurance.She added: ‘Working together we have jointly discharged our responsibility to deliver a quality prosecution service to the court, the wider community and particularly to victims and witnesses. In our view that should continue on 6 January.’last_img read more

Profession welcomes return of jury trials – but warns against court rush

first_imgFind advice and updates here. Please see the Gazette’s dedicated coronavirus page here >> *The Law Society is keeping the coronavirus situation under review and monitoring the advice it receives from the Foreign & Commonwealth Office and Public Health England. The legal profession has cautiously welcomed news that jury trials will start again next week, but said the safety of court users is paramount.The lord chief justice, Lord Burnett of Maldon, announced this morning that new jury trials may begin in a small number of courts in the week commencing 18 May. Special arrangements will be in place to protect participants from coronavirus. New juries will be sworn in at the Old Bailey in London and Cardiff Crown Court, with a small number of trials expected to take place initially. More courts around the country are currently being assessed.  Lord Burnett of Maldon: New jury trials due to begin under ‘special arrangements’Source: Michael Cross To facilitate social distancing, a second courtroom will be provided, linked by closed circuit TV, to enable reporters and others to watch proceedings. Court staff will also supervise entrances and exits to ensure all necessary cleaning takes place.Law Society president Simon Davis welcomed the announcement. He said: ‘With efforts to maintain good hygiene, appropriate distancing, and compliance with all other relevant guidance – jury trials should be resuming as soon as it is safe to do so.‘The extent of the roll-out, particularly with new trials, should be determined by the number of courts which are able to meet those requirements. Some courts – i.e. those with newer, larger courtrooms – will likely find it easier than others to adapt. We must avoid a rush to open courts where it is not yet possible to ensure adequate safety and the right protections.’Bar Council chair Amanda Pinto QC was also ‘encouraged’. She said: ‘It is reassuring that efforts to restart jury trials have involved a painstaking and cautious approach, that prioritises practical measures to ensure the safety of all those involved in the delivery of criminal justice.‘The decision has not been made lightly. The Bar Council sees these first steps in managing and, then, we anticipate, as soon as is safely possible, rolling out jury trials more broadly across the nation, as a positive sign way that criminal justice matters.’However, the Criminal Bar Association stressed the importance of safety checks. Caroline Goodwin QC, chair of the CBA, said: ‘The criminal bar knows that neither the judiciary, nor the Crown Prosecution Service, nor HM Courts & Tribunals Service, would wish to place anyone at risk, but they need to have clear and consistent messaging which indicates that safety checks meet the requisite standards, and that social distancing can be maintained.‘As regards the resumption of trials, the CBA will be taking its next cue from the judicial committee chaired by Mr Justice Edis, which remains underway, and will ensure that HMCTS can oversee the safe commencement of a limited and managed reopening of the Crown court in respect of jury trials.’A judicial working group, under Mr Justice Edis and reporting to the lord chief justice, is looking at how jury trials can be more widely restart around the country, amid concerns that a growing backlog of cases will cripple the system. The crown court backlog stood at 37,000 cases before the crisis and is believed to have grown significantly in the past two months.last_img read more

Final Form from Sampa the Great might be the best hip hop tune of 2019

first_imgSampa the Great (real name Sampa Tempo) has already been enjoying some success in the Australian Hip Hop scene but now she’s starting to make waves over here too. Born in Zambia and raised in Botswana her African roots carry through to her music and especially her lyrical content.From 2014 she was based in Australia and this is where her music career started to take off. Her first mixtape was released in 2015 which Tempo described as “a search for creativity, laughter, purpose and rhythms” She followed this up with a few more singles in the same year.Credit: Sampa the Great / Ninja TunesIn 2017 she released the single Everybody’s Hero with Estelle and also released her debut EP HERoes Act 2. Between then and now there have been several more singles and her debut album The Return is set to be released on 13th September 2019.I first heard Sampa the Great on Radio 6 and I was immediately captivated by the single Final Form. Musically the track is very catchy but once you start to listen to what Tempo is saying you can tell that she’s serious about what she’s doing, I get the impression music isn’t being used as a vehicle to fame and fortune, rather it’s being used to get her point across regarding the inequalities in life whether they be due to race or gender.View the Final Form video below:She is a great spokeswoman not only for celebrating her African roots and influences but also celebrating being a woman in the rap game. I was relieved when I saw the video for Final Form. First off it’s a celebration of African culture and being black and it’s great to see a rap artist saying true to their roots. Second, there is no sexualisation in the video at all, which female stars are often, if not forced then certainly, encouraged to embrace. I love the fact that she is sticking to her guns and what’s important to her.Put simply, Sampa the Great’s music does her talking for her and I for one want to hear more of what she has to say.last_img read more

Caribbean expert warns of Caribbean heat season

first_imgPHILLIPSBURG, St. Maarten, CMC —  A Caribbean climatologist says that while the Caribbean is best known for having wet, dry and hurricane seasons, a little known fact is that the region also has a distinct heat season.May – October is heat seasonCédric Van Meerbeeck, climatologist at the Barbados-based Caribbean Institute for Meteorology and Hydrology (CIMH) says that since about 1995, the Caribbean has had a distinct heat season which lasts from about May to October and is forecast to be more intense this year that the last two years.“But the heat season is something that didn’t happen in the past. Yes, people feel more comfortable and sometimes even cold around Christmas time and you know that it gets hotter towards September. But it’s not really common knowledge that there is a six-month period that noticeably warmer than the other part of the year and that is May to October….Impacting health“And during that heat season, you find that the levels of heat discomfort and heat stress [increases] so that’s impacting your health, also the health of some animals,” Van Meerbeeck said, adding this has implications for comfort levels as well as major sectors in the region, such as tourism and agriculture.He told the Caribbean Media Corporation (CMC) on the side-line of the Caribbean Climate Outlook Forum (CariCOF) that while the heat season peaks in September, the region has its most heat waves between August and October.“Heat waves might not look as extreme as they are in some desert areas or some part of the United States and other regions. However, they do impact us because mostly that’s also the time of the year when the humidity is high,” Van Meerbeeck explained.“When humidity is high, your body doesn’t cool as effectively as when the air is quite dry and so you feel more heat stress even though the temperature does not increase immensely,” Van Meerbeeck said, urging people to stay as cool as possible, especially from August onward.The climatologist said that for the first half of the heat season, the air is still relatively dry, therefore, the temperatures are not necessarily so uncomfortable.Second half of heat season is worse“But it is really that second part of the heat season that we want to warn against. Keep cool; don’t go in the sun in the middle of the day; seek shade, seek ventilation in your homes.“If you have an AC, make sure you run the AC while you sleep so that your brain and your body can recover better and that you can function normal in the face of the heat,” the climatologist advised.“Last year, we were quite fortunate that there were not many heat waves. It was not that brutal. A comparable season would have been 2016 when we really had a lot of heat between August and October.”Caused by rising ocean temperaturesVan Meerbeeck said the cause of the higher temperature is the rising temperatures of the ocean, which releases heat into the atmosphere during the heat season.“It doesn’t change the weather much from day to day, but over longer periods of time, it does affect the amount of energy that is in the atmosphere and therefore that is the temperature that you feel,” the climatologist said, adding this is definitely linked to climate change.“And this is one of the clearest links that we observe in the Caribbean beside sea level rise. The increasing temperature now means that even though we didn’t have a heat season outside of maybe August to October in the past, now you find that heat waves actually occur for a longer period of time every year in the warmer years particularly.“But now, in the cooler years, you now have heat waves. That didn’t used to be the case up until about 1995. It’s really something recent, where the trend of temperate going up with climate change is really affecting the heat level that we have in the season.”He said this has implications for agriculture and fisheries, especially the livestock subsector and fish, especially in the northern Caribbean, that are sensitive to the heating of the sea surface.“But for livestock, it’s important to also provide cooling for them. For us that is important. Maybe ethically that’s one thing but also in terms of our food security, our protein stock really comes from chicken and chicken are amongst the most sensitive animals to excessive heat especially broilers.”Van Meerbeeck said it is a good practice to keep poultry birds cool “So you can make sure that your chicken stock does not reduce and does not experience that heat stress which leads to less protein being available at a reasonable cost for us.”As regards to tourism, the climatologist said that heat is not that much of a problem as long as awareness is built with tourists.“But they should really do their best to keep cool whenever they can, stay hydrated, seek the shade, seek well-ventilated places; if you go in the sun, don’t go in the middle of the day,” Van Meerbeeck said, adding that hotels should also remind tourists to stay cool.last_img read more