Heavy coffee drinkers are more sensitive to the smell of coffee, study finds

first_imgEmail Share LinkedIn Share on Facebook Share on Twittercenter_img Pinterest “However, most of our richer experiences are multisensory, so it seems likely that other senses must also play a role in the addictive process,” Stafford explained.The researchers conducted two experiments to examine how well participants with varying levels of coffee consumption could detect coffee-related odors.The first experiment, which included 62 participants, found that those who drank the most coffee were able to identify coffee at weaker concentrations and were faster to identify the odor. In addition, those who consumed more caffeine were more likely to indicate they had a stronger craving for caffeine.“More interestingly, higher craving, specifically that which measured the ability of caffeine to reverse withdrawal symptoms such as fatigue, was related to greater sensitivity in the odor detection test,” Stafford said in a news release.The second experiment, which included another 32 participants, found that caffeine consumers were more sensitive to the coffee odor but were not more sensitive to other odors.Stafford told PsyPost that the findings show how “fairly basic processes in olfactory detection are linked to complex behavior such as drug consumption and addiction.”“So, it was not just a case of more exposure to a smell (coffee) made people better at detecting that odor, but that their ability to detect the odor was related to their habitual consumption and craving.”“In addition to further work needed in replicating these findings, particularly the craving aspect, I think it would be interesting to explore whether therapy could be developed to help people kick unwanted drug habits. Research from another laboratory has suggested that creating an aversive response to a specific odor is relatively quick and easy in humans, which offers a possible protocol of how a therapy could be developed,” Stafford added.The study, “Higher Olfactory Sensitivity To Coffee Odour In Habitual Caffeine Users“, was authored by Lorenzo D. Stafford, Kit Damant, Sophie Ashurst, and Matt Parker. Habitual coffee drinkers are able to detect the odor of coffee at lower thresholds and are also faster to identify it, according to new research published in Experimental and Clinical Psychopharmacology. The findings provide new insight into sensory changes that accompany drug consumption.“Many years ago, I completed a PhD on the topic of caffeine and the general importance placed on the sensory (especially smell) aspects of coffee, which all planted the seed (or bean!) for a possible study. More recently, I begun thinking about the role of our sense of smell in drug consumption and addiction,” said study author Lorenzo Stafford, a senior lecturer in psychology at the University of Portsmouth.“Most of the research in this area is dominated by visual processes, in particular showing how cues associated to drugs (e.g. packet of cigarettes, bottle of beer) become conditioned in such users. That work has been useful in explaining how in recovering addicts, long after the withdrawal symptoms have subsided, when exposed to such cues, they can nevertheless relapse to craving and consuming the drug. Hence, though a powerful driver, addiction is not just about reversing withdrawal symptoms.”last_img read more

News Scan for Mar 31, 2015

first_imgPAHO chikungunya count rises by more than 32,000The number of chikungunya infections in the Americas has increased to 1,343,372, a rise of 32,504, the Pan American Health Organization (PAHO) said in its latest update. The bump in cases was slightly higher than the 28,768-case increase recorded the week before.PAHO’s latest count includes 1,310,925 suspected, 28,910 confirmed, and 3,537 imported cases. Most of the imported cases are from the United States, which has 2,549,13 more than the previous week.The US Centers for Disease Control and Prevention (CDC) said in a Mar 24 update that so far 68 chikungunya cases, all of them travel related, have been reported in 19 states so far this year. No locally transmitted cases have been reported. US territories have reported 52 chikungunya cases this year, all of them locally transmitted infections in Puerto Rico and the US Virgin Islands.Most of the increase this week came from Nicaragua, which submitted 10 weeks’ worth of data, and Colombia.The death toll from the disease remained the same at 184.Mar 28 PAHO update Mar 24 CDC update Saudis report another MERS case; camel serum suggested as treatmentSaudi Arabia reported another MERS-CoV (Middle East respiratory syndrome coronavirus) case today, while researchers raised the possibility of using camel antibodies to treat MERS patients.The latest patient is a 65-year-old expatriate woman in Riyadh who is in stable condition, the Saudi Ministry of Health (MOH) reported. She is not a healthcare worker and had no contact with other MERS patients in healthcare or community settings, but the statement did not indicate whether she had any contact with animals.The MOH also announced the death of a 57-year-old Saudi man in Hofuf whose case was reported earlier. In addition, the ministry noted the recovery of a 50-year-old male expatriate in Najran.The latest events raised the MOH’s cumulative MERS count to 973 cases, with 422 deaths, 532 recoveries, and 19 patients still in treatment or home isolation. Mar 31 MOH statementMeanwhile, researchers reported recently in the Journal of Virology that they used antibodies from camels to protect mice from MERS-CoV and to help infected mice recover from the disease.The authors, from the United States and China, wrote that serum from recovered MERS patients may be useful for treating infected persons but is not readily available, and that most camels in the Arabian Peninsula carry MERS-CoV antibodies because of past infections. They used serum from camels to treat mice infected with human MERS-CoV isolates.”The study, a successful proof-of-concept study, showed that prophylactic or therapeutic treatment with high-titer MERS immune camel sera diminished weight loss and pathological changes in lung tissues, and cleared the infections in the mice,” says a press release from the American Society for Microbiology (ASM), publisher of the Journal of Virology.”Our results suggest that these antibodies might prove therapeutic for MERS patients, and might protect uninfected household members and healthcare workers against MERS,” corresponding author Stanley Perlman, MD, PhD, said in the release. He is a professor in the departments of microbiology and pediatrics at the University of Iowa.Mar 18 J Virol study Mar 30 ASM press release Study: Sofosbuvir for hepatitis C cost-effective only in sickest patientsFor cost-effectiveness, oral sofosbuvir-based treatment for hepatitis C virus (HCV) types 2 and 3 would best be reserved for only those patients with advanced liver disease or for whom other treatments have failed, say the authors of a study published yesterday in the Annals of Internal Medicine.The researchers, from Boston Medical Center (BMC), simulated clinical outcomes, measured as quality-adjusted life years (QALYs) gained, and costs in 2013 US dollars for eight treatment strategies, including sofobuvir-based treatments, the first all-oral treatment approved for US HCV infections. They also calculated the incremental cost-effectiveness ratio (ICER) of treatments by dividing additional costs of each treatment into QALYs gained over the next less expensive treatment.They found that for patients with cirrhosis, the ICER of sofosbuvir treatment was less than $100,000 for each QALY gained whether or not patients have been treated previously with other therapies, a cost commonly cited as the “US willingness-to-pay threshold” per QALY gained, say the authors. By contrast, in noncirrhotic HCV patients who are treatment-naive, the cost was calculated as more than $200,000 per QALY gained.The authors give two reasons for the non-cost-effectiveness of sofosbuvir treatment in treatment-naive noncirrhotic HCV patients. First, pegylated interferon-ribavirin, which is less-expensive, has an efficacy rate of about 80% in these patients but is not an option in treatment-experienced patients. Second, the risk of death from HCV is low in patients without cirrhosis, and not all develop cirrhosis, so sofosbuvir therapy does not translate directly into substantial increases in life expectancy in this group.In addition to limiting the candidates for sofosbuvir treatment, the authors say the cost-effectiveness of the treatment could be improved by lowering the cost of the agent. “At its current cost, access to sofosbuvir will likely be unequal and restricted and will limit the number of people ultimately cured of HCV infection in the United States,” they say.Mar 30 Ann Intern Med study abstract Mar 30 BMC press release Resistant infections tied to endoscopes thought to be fully decontaminatedCurrent industry standards for cleaning and maintenance of endoscopes are insufficient for complete decontamination, say the authors of a report on a cluster of antibiotic-resistant Escherichia coli (CRE) infections published yesterday in Infection Control & Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America (SHEA).The cases of 49 patients with AmpC E coli infection who were patients at a hospital in Washington state from January 2012 to August 2013 were reviewed. Gene sequencing showed 35 (71%) of them to have a strain of bacteria with an identical mutation, including all 10 with carbapenem-resistant (CR) infection.All 35 had complicated biliary or pancreatic disease and had undergone endoscopic retrograde cholangiopancreatography (ERCP) at least once during the study period. Mortality at 30 days was 16% overall and 56% for the CR patients.An evaluation of reprocessed ERCP scopes at the hospitalshowed that 2 of 8 were contaminated by the same bacteria on pulsed-field gel electrophoresis. They had all been cleaned at a level exceeding the manufacturer’s guidelines. Environmental cultures were negative, and no breaks in infection-control procedures were known.A press release from SHEA says the hospital has taken “costly and extraordinary measures,” including quarantining and culturing ERCP scopes after cleaning but that even that has not been entirely successful.”We suspect endoscope-associated transmission of pathogenic bacteria might be both more common than recognized and not adequately prevented by current endoscope reprocessing guidelines,” conclude the authors. They suggest re-evaluation of endoscope design and of reprocessing standards and say endoscopists should inform patients of the risk for endoscope-related bacterial transmission.The report comes in the wake of reports in February of antibiotic-resistant infections linked to the use of reusable duodenoscopes in seven patients at a hospital in Los Angeles.Mar 30 Infect Control Hosp Epidemiol study abstract Mar 30 SHEA press release Related Feb 19 CIDRAP News itemlast_img read more

COVID-19 Update Turks and Caicos Islands

first_imgThe Ministry of Health would like to advise the public that as at 12am on 27th May, 2020: Oct 16, 2020 A suspected person is someone who meets the case definition as outlined by WHO and CARPHA – and is experiencing symptoms.A person in quarantine is an individual on island who may have come in proximity to suspected or confirmed cases – and have not exhibited symptoms. The Ministry of Health takes this opportunity to remind the public to continue following the advice and guidelines from the ministry. Persons are also reminded of offenses committed under section 27 of the Emergency Powers (COVID-19) (nO.4) Regulations 2020 in regard to false Statements/information. You do not have to be the originator of the statement/information in order to be charged under the law. Six Eastern Caribbean countries deemed safe for travel – CDC Oct 16, 2020 Please note the following definitions: More deaths from COVID-19 recorded in CARICOM countries,… CMO says Saint Lucia at critical stage of COVID-19 outbreak There continues to be no new positive cases recorded. Confirmed positive cases currently stand at twelve (12); with the total number of recoveries from covid-19 at ten (10), and the TCI continues to record one covid-19 death. For more information, please visit the Ministry of Health website, www.gov.tc/moh/coronavirus; email: COVID19@gov.tc; or call our hotline numbers, (649) 232-9444 and (649) 333-0911, if you or someone you know has symptoms or signs of COVID-19. Share this:PrintTwitterFacebookLinkedInLike this:Like Loading… Let’s continue to reduce the risk by: 1. Washing our hands for 20secs or more 2. Practicing social distancing 3. Prepare your home, office and other surroundings by following the advice of the Ministry of Health and other credible health agencies.center_img St. Lucia records more cases of COVID The number of persons in quarantine/observation has increased to 25. This includes: A suspected case (1), contacts of suspected cases (10), and travellers (14) – Seven (7) of the travellers are currently being quarantined at a non-medical facility, and are not sick. Persons under observation/quarantine, that are not confirmed or suspected cases, are either not displaying symptoms or have not met the case definition. The increase in quarantine/observation numbers is as a result of travellers into the tci who have been added to quarantine/observation status. To date, a total of 663 individuals have been released from quarantine/observation status.  You may be interested in… Oct 15, 2020 The Turks and Caicos has experienced little change in its covid-19 position since the previous update. No new positive or negative results have been received over the past 24hrs. To date, the TCI has received a total of one hundred and twenty-nine (129) test results, with one hundred and seventeen (117) confirmed to be negative and twelve (12) positive confirmations. Persons confirmed not to have COVID-19, and their contacts, were moved from quarantined status and asked to continue following proper guidelines from the Ministry of Health. Oct 15, 2020 Suspected cases have remain at two (2). Both cases are TCI residents experiencing relevant symptoms without a history of contact with confirmed cases. One suspected case passed away. Current suspected cases have met the WHO case definition for a suspected case of COVID-19. Samples have been collected and sent for testing. COVID-19 Update Turks and CaicosThe Ministry of Health would like to advise the public that as at 12am on 18th May, 2020: No changes have occurred in the Turks and Caicos’ covid-19 position since the previous update. Confirmed positive cases remain at twelve (12); with the total number of recoveries from covid-19 at ten (10),…May 19, 2020In “General”Turks and Caicos Islands COVID-19 Update April 19The Ministry of Health would like to advise the public that as at 12am on 19th April, 2020: THE TURKS & CAICOS CONTINUES TO RECORD ONE COVID-19 DEATH. THE TOTAL NUMBER OF CONFIRMED POSITIVE CASES REMAINS AT ELEVEN (11). Two confirmed positive cases are currently under hospital care. HOWEVER, A PATIENT FROM…April 19, 2020In “General”COVID-19 Update Turks and Caicos IslandsThe Ministry of Health would like to advise the public that as at 12am on 14th May, 2020: The Turks and Caicos has seen no change in its COVID 19 position over the ast 24 hours. No new confirmed cases have been recorded. Confirmed positive cases currently stand at twelve (12);…May 15, 2020In “General”Share this on WhatsApplast_img read more

Auto shutdown system from CONCOA enhances safety

first_imgGet instant access to must-read content today!To access hundreds of features, subscribe today! At a time when the world is forced to go digital more than ever before just to stay connected, discover the in-depth content our subscribers receive every month by subscribing to gasworld.Don’t just stay connected, stay at the forefront – join gasworld and become a subscriber to access all of our must-read content online from just $270. Subscribelast_img

Short and Tweet

first_imgGet your free guest access  SIGN UP TODAY Subscribe now for unlimited access Subscribe to Building today and you will benefit from:Unlimited access to all stories including expert analysis and comment from industry leadersOur league tables, cost models and economics dataOur online archive of over 10,000 articlesBuilding magazine digital editionsBuilding magazine print editionsPrinted/digital supplementsSubscribe now for unlimited access.View our subscription options and join our community To continue enjoying Building.co.uk, sign up for free guest accessExisting subscriber? LOGIN Stay at the forefront of thought leadership with news and analysis from award-winning journalists. Enjoy company features, CEO interviews, architectural reviews, technical project know-how and the latest innovations.Limited access to building.co.ukBreaking industry news as it happensBreaking, daily and weekly e-newsletterslast_img read more

Pan Ocean back in black

first_imgPan Ocean has recovered from the huge loss of USD1.76 billion it posted during 2013, despite revenue falling by 36 percent year-on-year during 2014 to USD1.56 billion. The line’s equity was also up by 466.9 percent from USD228.3 million in 2013 to USD1.294 billion in 2014. HLPFI reported during December 2014 that Singapore headquartered chicken processor, Harim Group, is heading up a consortium of organisations to buy Pan Ocean in a deal worth in the region of USD968 million. www.panocean.comwww.harimgroup.comlast_img read more

Grieg Star completes refinancing

first_imgLoans with original expiry set for 2017/2018 were extended with five or more years, with new expiry in 2022 or beyond. The refinancing was completed with five European banks.Together with a sale and leaseback transaction completed earlier this year, a total of USD400 million of financing facilities has now been refinanced, said Grieg Star.The shipping line operates 45 open hatch and dry bulk vessels, of which 31 vessels are on the balance sheet. The completed refinancing ensures long-term financing for all ships owned by the company.In addition to extending maturities, the USD400 million refinancing will entail a cash release of more than USD50 million. Grieg Star stated that the added liquidity will, together with existing liquidity reserves, ensure strong cash reserves and financial strength going forward.Grieg Star added that it has previously secured financing of newbuilding commitments and currently has no unfunded future capital expenditures.”We are very pleased to have received continued support from quality financiers like DNB, Nordea, SR-Bank and ABN AMRO, including establishing new relationships with Credit Suisse,” said Grieg Star ceo Camilla Grieg.”This refinancing reflects our strong bank relationships and the importance of having capital sources available in a challenging market like what we see today.”  www.griegstar.comlast_img read more

Proportionality hits Brian May’s costs claim in neighbour dispute

first_imgA costs claim brought by rock musician Brian May against developer Wavell Group Limited is limited to 20% of the amount sought, a court has decided in the latest application of the principle of proportionality in civil costs.Costs judge Master Rowley determined that costs allowed in the case should be reduced to £35,000 plus VAT. May had sought £208,236.54 including VAT. May (pictured) and his wife, who live in Kensington, London, brought proceedings in the county court for nuisance caused by a neighbour’s basement development.The subsequent costs claim was disputed on grounds of being both unreasonable and disproportionate to the issues. The Mays had accepted compensation of £25,000 at an early stage in the claim.Rowley reduced the costs in two steps. First, cutting the claim to £99,000 as a figure that was more ‘reasonable’. The second reduction was made after a proportionality test, introduced by Lord Justice Jackson’s civil litigation reforms, was applied. The Mays had instructed Simon Farrell QC for the claim through a direct access scheme.Boodle Hatfield partner Colin Young, who acted for Wavell, said: ‘Costs incurred should be tightly focused on the issues at large in the proceedings. ‘If any party wishes to pursue matters outside of that focus, they cannot reasonably expect to recover the costs of such matters if they are successful in their case. The courts are likely to scrutinise ever more carefully the costs incurred.’Farrell told the Gazette: ‘In this case 25% of the total costs claimed comprised acoustic expert fees and not legal fees. The Master found that approximately £97,000 costs were reasonably and necessarily incurred in bringing and pursuing the claim to settlement. He then went on to apply the new proportionality test to that figure of the costs which he had found to be reasonable and reduced it further. Proportionality and costs is a developing area and the Master described it as being in a “transitional phase”. This case raises an important point of principle.’ An appeal is being considered, he added.last_img read more

Custom import duty reduced on barrels for Christmas

first_img Sharing is caring! LocalNews Custom import duty reduced on barrels for Christmas by: – December 5, 2012 52 Views   7 comments Share Tweetcenter_img Share Share The Dominica government has announced that it will again, this year, remove the customs import duty and service charges on obtaining barrels for the Christmas season.Minister with the portfolio for Ports, Rayburn Blackmoore announced on Wednesday December 5th that this is part of his government’s goal to “facilitate people, more so the downtrodden”.“It has become one of our traditions every year to have the barrels rolling”.“To qualify for this concession the barrels must be valued at EC $1500.00 and the items in the barrels must be for personal use and should not be for commercial purposes”.The contents which will be allowed are “mainly food stuff, limited items of clothing and toys”.Persons will be charged a flat rate of $10.00 for both barrels.However, persons will be expected to pay the VAT as well as the environmental levy charge which is 1.5% of the value of the cost of the package.With regards to the definition of a barrel to avoid any confusion, Blackmore said these are “boxes, packages, and drums”.Persons wishing to take advantage of this concession are advised that they “cannot come and clear your two barrels today and come back next week, you’re not qualified for that”.“You are qualified for two barrels for the implementation period” at a concessionary rate.He is hopeful that “the public will continue to maximize on that opportunity make use of that facility”.This concession will be available from tomorrow, Thursday December 6th until January 9th, 2013.He also complimented the staff of the Dominica Air & Sea Ports Authority (DASPA) for “being very, very efficient and we’re hoping to see the same level of cooperation and collaboration with the Customs this year”. Dominica Vibes Newslast_img read more

NXP Introduces High-Security IC for Contactless Smart City Applications

first_imgNXP Semiconductors announced the new MIFARE DESFire EV3 IC, the third generation of its proven contactless MIFARE DESFire portfolio. This new generation of IC brings next-generation performance, advanced security and seamless integration of mobile services for a new era of security and connectivity in smart city services. In addition, it offers greater operating distance, improved transaction speed and is also back compatible. In combination with its advanced security features, the new IC delivers faster, more secure transactions that are truly contactless, such as paying for parking, accessing offices or campuses and using other essential city services—all touch-free.With proven success over the past 25 years, NXP’s MIFARE product portfolio is at the heart of smart city installations worldwide. The MIFARE DESFire EV3 IC builds upon the portfolio’s heritage of powering mass transit ticketing by also delivering the next level of convenience for end users and reliability for service providers. NXP is committed to providing riders with secure, reliable and flexible transport ticketing solutions and with NXP’s proven MIFARE DESFire products, it can continue to support riders with a seamless transport experience that is both safe and convenient.NXP’s IC provides multi-application support and delivers a wide array of enhanced features that allows transit agencies, access control solution providers, and system integrators to collaborate on new business models and scale their services.An extensive set of security features in the MIFARE DESFire EV3 IC provide more ways to protect data and help ensure privacy. The IC hardware and software are certified to Common Criteria EAL 5+, and the IC supports a broad choice of open crypto algorithms. A card generated MAC helps to securely authenticate transactions, and a new Transaction Timer feature helps mitigate man-in-the-middle attacks so it’s harder for an attacker to interfere with the transaction. Additionally, its new Secure Unique NFC (SUN) messaging feature offers a more secure method for maintaining data confidentiality and integrity. Each time a card, phone or ticket is tapped with the SUN featured enabled, a tap-unique authentication message and crypto-secure URL are generated that can be sent to a server for verification, which makes taps unclonable.Support for MIFARE DESFire EV3 will be integrated into NXP’s MIFARE 2GO cloud service, which manages digitized MIFARE product-based credentials and helps streamline mobile integration via NXP’s ecosystem. With this, smart city services can be seamlessly deployed to NFC-enabled smartphones, wearables and other mobile devices.With the launch of MIFARE DESFire EV3, NXP is laying the foundation for a new level of connected smart city services that are form factor independent and can be available on a traditional smart card or mobile device. The security features of the IC help prevent fraud and theft and, combined with its ability to support a broad range of applications, the IC paves the way for managing many other smart city services beyond transit and access control. NXP is proud to empower society with our contactless solutions for broad scale use, as the worldwide impact of COVID-19 makes contact-free transactions a necessity.For simplified deployment, each MIFARE DESFire EV3 IC is pre-configured with keys to enable delegated application management, which supports seamless, over-the-air updates to already deployed smart cards using NFC-enabled smartphones.In addition, NXP’s upcoming MIFARE Plus EV2 IC will provide a drop-in replacement for upgrading existing MIFARE Plus and MIFARE Classic product-based installations to higher security.Click here for more on MIFARE DESFire EV3 IClast_img read more